NEUROSURGERY ARTICLES
CYBERKNIFE STEREOTACTIC RADIOSURGERY FOR SPINAL TUMORS
by Laura Paré, M.D.
Prior to the development of radiosurgery for
spinal tumors, conventional radiation therapy
was used and resulted in large radiation
doses being given to important normal tissues
located near the tumor, such as the
spinal cord and nerves. Radiosurgery is the
process by which a tumor can be precisely
and completely destroyed using high tumorkilling
doses of radiation without significantly
damaging the surrounding normal tissues.
One of the most accurate methods of treating
spinal tumors with radiosurgery is by
using the Cyberknife® (Accuray, Inc.,
Sunnyvale, CA). The Cyberknife® was
approved by the US Food and Drug
Administration in 2001 for use on the spine.
Spinal tumors can be either benign or malignant.
In order to determine whether a
patient is a candidate for Cyberknife®
radiosurgery, they must first consult with a
neurosurgeon and then a radiation oncologist
who have special training in radiosurgery and Cyberknife® technology.
Then the patient will need small, 3-4 mm, metal markers
called fiducials to be implanted into the spine in the region of the
tumor during a short, outpatient surgery. The fiducials are implanted
using minimally invasive spinal surgery techniques.
Next, the patient undergoes a CT scan and an MRI scan of the spinal
tumor after the fiducials are implanted. The neurosurgeon, radiation
oncologist, and radiation physicist, together,
then plan the radiosurgery treatment using
the CT scan, MRI scan, and sophisticated
computer software that allows the maximum
dose of radiation to be given to the
tumor in a very accurate fashion, while minimizing
the radiation dose to the spinal
cord, nerves, and other important tissues
nearby.
Finally, the patient comes to the
Cyberknife® Center and undergoes the
radiosurgery treatment as an outpatient.
The patient lies comfortably on a special
table at the Cyberknife® Center while the
treatment is given. Treatments generally
last from 30 minutes to 2 hours, and are
given in one to three sessions depending on
the size and complexity of the tumor being
treated. During the treatment, x-rays are
taken of the spine and the fiducials frequently.
This allows the computer program
to compensate for any movements of the patient during the treatment
to maintain maximal accuracy during radiosurgical treatment.
Spinal radiosurgery is well-tolerated by most patients.
For information about the Cyberknife® here in Orange County, log
onto www.newportdiagnosticcenter.com/cyberknife.html. For more
information about Cyberknife® in general, log onto
www.accuray.com.